Most women just want to know...

• Minoxidil can cause additional shedding at first, as your hair growth cycle is resetting, allowing new hair to grow in. This improves with continued use, which means the treatment is working. Shedding is totally normal in the first 2-4 weeks of treatment, so hang in there and trust the process.
• With oral minoxidil, you may notice an extra hair or two growing in other places on your face or body. We know that additional hair growth isn't ideal, but it's a possible side effect. That said shaving, plucking, or waxing should do the trick.

Always reach out to a provider if you experience any side effects. Questions and follow-up care with a licensed provider are included with Locklab.

Important safety information and warnings

Who should not use oral minoxidil?

• Do not use oral minoxidil if:
• You have pheochromocytoma, a tumor in the adrenal gland.
• You have a known allergic reaction to oral minoxidil.
• You are pregnant, planning to become pregnant, or breastfeeding.

What are the most common potential side effects of oral minoxidil?

• Elongation, thickening, and enhanced pigmentation of fine body hair (called: hypertrichosis)
• Salt and water retention
• Tachycardia (increased heart rate)


How should I take oral minoxidil?

Oral minoxidil can be taken with or without meals. You should take oral minoxidil exactly as prescribed and you should not change your dosing regimen without discussing it with your provider first.

What should I tell my Locklab-affiliated provider before using oral minoxidil?

• Oral minoxidil has certain drug interactions. It’s important to tell your Locklab-affiliated provider all of the medications you are currently taking, including prescription, over-the-counter medications, vitamins, and herbal and dietary supplements.  Some medications to watch out for include: Guanethidine - Do not take oral minoxidil if you take guanethidine.
• It’s important to share your entire medical history with your provider. In particular, tell your provider if you have a past history of:
  • Heart disease, including stroke, heart attack, pericarditis, or congestive heart failure
  • Kidney disease
  • Liver disease
• Tell your provider if you are pregnant, planning to become pregnant, or breastfeeding.

Withholding or providing inaccurate information about your health and medical history in order to obtain treatment may result in harm, including, in some cases, death.

Rare Cardiac Effects

• Minoxidil can cause pericardial effusion, the accumulation of too much fluid in the sac that surrounds the heart (pericardium). Pericardial effusion can progress to tamponade which increases pressure on the heart and keeps it from beating properly. This can result in sharp chest pain and difficulty breathing. Seek emergency treatment if this occurs.
• When using minoxidil to treat high blood pressure, it should be reserved for patients who do not respond adequately to maximum therapeutic doses of a diuretic (water pill) and two other blood pressure lowering drugs.
• When using minoxidil to treat high blood pressure, it must be administered under close supervision, usually with a beta-blocker to prevent increased heart rate (tachycardia) and increased the stress put on the heart muscle (myocardial workload). It must also usually be given with a diuretic to prevent serious fluid accumulation.
• Patients with malignant hypertension and those already receiving guanethidine should be hospitalized when minoxidil is first administered so that they can be monitored to avoid too rapid decreases in blood pressure.

What are the most serious side effects that I or a caregiver should monitor for when taking oral minoxidil?

• Salt and water retention: Monitor for fluid retention and increase in body weight. If you quickly gain five or more pounds, or if there is any swelling or puffiness in the face, hands, ankles, or stomach area, this could be a sign that you are retaining body fluids. Stop the medication and contact your Locklab-affiliated provider or your in-person provider.
• Increased heart rate (tachycardia)/palpitations: You should measure your heart rate by counting your pulse rate while you are resting. If you have an increase of 20 beats or more a minute over your normal pulse, or you are experiencing palpitations, stop the medication and contact your Locklab-affiliated provider or your in-person provider immediately.
• Pericarditis, Pericardial Effusion and Tamponade: There have been reports of pericarditis in association with the use of oral minoxidil. Oral minoxidil can also cause an accumulation of fluids in the sac surrounding the heart. Monitor for sharp pain in the chest, arm, or shoulder; signs of severe indigestion; or shortness of breath, dizziness, lightheadedness, and fainting. These could be signs of serious heart problems and you should seek immediate emergency care.
• Hazard of Rapid Control of Blood Pressure: A sudden or too large of a drop in blood pressure in people with very high blood pressure can lead to fainting, heart attack, and loss of blood flow to certain organs.

If you are experiencing a medical emergency, call 911 or seek immediate medical attention.‍

This information is not comprehensive. Please see the full Prescribing Information for complete safety information.